PDRN (Polydeoxyribonucleotide) therapy, commonly known as Rejuran or "salmon DNA injections," has exploded in popularity across Korea and is now the most in-demand skin treatment of 2026. Derived from salmon DNA fragments, this treatment works at a cellular level to rejuvenate skin from within.
What Is PDRN and How Does It Work?
PDRN is a biological molecule extracted from salmon DNA that closely resembles human DNA structure. When injected into the skin, it activates cell regeneration and repair mechanisms, boosting collagen and elastin production naturally.
- Cellular regeneration: Activating dormant skin cells to produce new, healthy tissue
- Anti-inflammatory effects: Reducing redness and calming irritated skin
- Improved microcirculation: Enhancing blood flow for a natural glow
- Wound healing: Accelerating recovery from acne scars and damage
Clinical Benefits
Studies on PDRN therapy have demonstrated impressive results:
- 47% improvement in skin hydration after a full treatment course
- 33% increase in skin elasticity within 3 months
- Significant reduction in fine lines and wrinkle depth
- Visible improvement in acne scarring and skin texture
PDRN vs Other Skin Boosters
| Treatment | Main Benefit | Duration | Best For |
| PDRN (Rejuran) | Cell regeneration | 6-12 months | Overall skin quality |
| Profhilo | Deep hydration | 6 months | Dehydrated, aging skin |
| Exosomes | Advanced regeneration | 3-6 months | Anti-aging, repair |
The Treatment Process
- Consultation (15 min): AI-powered skin analysis to identify target areas
- Numbing (20 min): Topical anesthetic cream for comfort
- Injection (30-45 min): Micro-injections across the face
- Post-care: LED therapy or soothing mask
Most patients need 3-4 sessions spaced 2-4 weeks apart for optimal results.
Cost in Korea vs Abroad
- Korea: $180-275 per session
- United States: $500-800 per session
- Singapore: $400-600 per session
- Australia: $450-700 per session
Who Is PDRN Best For?
- Those with dull, tired-looking skin seeking a natural glow
- Patients with early signs of aging
- Anyone with acne scarring or uneven texture
- Patients aged 25-55 for preventive or corrective care
Results Timeline
- Week 1: Initial hydration boost
- Week 2-3: Improved skin texture noticeable
- Month 1-2: Visible glow, reduced fine lines
- Month 3: Peak results with improved elasticity
Related Articles
- Rejuran Healer: Is the Pain Worth the Glow?
- Korean Skin Boosters Complete Guide
- PN vs PLLA: Korean Bio-Lifting Treatments
- Top 5 Skin Treatments Trending in Korea
- Acne Scar Treatment in Korea
Interested in PDRN treatment? Contact MyDoc Korea for a free consultation and personalized treatment plan.
Medical Disclaimer
The information provided in this article is for general informational and educational purposes only and is not intended as, nor should it be considered a substitute for, professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment. Individual results may vary.